The Serum Pre-Clinical CartiLaps ® ELISA detects degradation products of C-terminal telopeptides of type II collagen (CTX-II) in animal serum. The test is intended For Research Use Only. Not for use in diagnostic procedures.
· Animal Models of Rheumatoid Arthritis and Osteoarthritis
· Easy, non-invasive quantification of cartilage degradation
· Strong association to indexes of joint damage, e.g. cartilage erosion
· Rapid assesment of chondroprotective drugs
· Early response in CTX-II is highly correlated to histological endpoint
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Code |
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Format |
96 Wells |
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Number of Tests per Kit |
41 in duplicate |
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Standards |
2 supplied (diluted to make 6) |
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Controls |
1 vial lyophilized |
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Specimen Type |
Serum or plasma (Synovial Fluid, EDTA) |
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Specimen Volume |
25 µL |
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Assay Range |
1.2-300 pg/ml |
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Precision |
CV's within run <8%; CV's between runs <13% |
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Total Assay Time |
2 hours 45mins (incubation time) |
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Detection Limit |
1.2 pg/mL |
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Precision |
<5.8% |
